550 5.7.606–649 Error: Microsoft 365: banned sending IP — Causes & Fix | InboxVerify
SMTP error code

550 5.7.606–649 — Microsoft 365: banned sending IP

Updated October 12, 2026 · By the InboxVerify team

Microsoft 365 (Exchange Online) blocked your sending IP because of its reputation. The bounce links to Microsoft's delisting portal at sender.office.com. (Outlook.com / Hotmail blocks use S3140 / S3150-style messages instead.)

Policy rejection · fixable

Common causes

  • Spam complaints or spam-trap hits from your IP
  • Shared IP used by other senders with bad practices
  • New IP with no reputation sending high volume

How to fix it

  1. Fix the cause (list hygiene, compromised accounts) first
  2. Request delisting at sender.office.com (the link is in the bounce)
  3. For Outlook.com / Hotmail blocks (S3150), use Microsoft's sender support form and monitor your IP in SNDS
Blacklist CheckerRun the right check for your domain or paste the full bounce message for a precise explanation.
Open Blacklist Checker →

Frequently asked questions

How long does Microsoft delisting take?

Often within a day after the request is approved; repeated listings take longer.